Yeast Infections from Lube? Here's How to Prevent them COCO CHEMISTRY Vaginal Lubrication: Vaginal Dryness, Vaginal Health, and More Condoms protect against unplanned pregnancy and most sexually transmitted infections, including HIV, gonorrhoea, chlamydia, and syphilis. Use only water or silicone based lubricant with a condom during vaginal and particularly anal sex Explainer: Using Saliva As A Lubricant During Sex Causes Genital Herpes Roundcheck Authenticity And Clarity Can Lube Cause A Yeast Infection? (And Ones That Won't)